Human FGF19 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

SKU: EZ1160

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: FGF19

Specificity: Natural and recombinant human FGF19

Background: FGF19, Fibroblast growth factor 19, is a protein that in humans is encoded by the FGF19 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. The FGF19 gene is mapped to 11q13.3. The deduced 216-amino acid FGF19 protein contains asignal sequence and 2 cysteine residues that are conserved in the FGF family. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. FGF19 stimulates hepatic protein and glycogen synthesis but does not induce lipogenesis. The effects of FGF19 are independent of the activity of either insulin or the protein kinase Akt and, instead, are mediated through a mitogen-activated protein kinase signaling pathway that activates components of the protein translation machinery and stimulates glycogen synthase activity.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: L25-K216

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Reference:

Uniprot ID: O95750

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 9965

Protein Name: Fibroblast growth factor 19

Gene Full Name: fibroblast growth factor 19

Synonyms: FGF 19; FGF19; fibroblast growth factor 19