Human Erbb Receptor Feedback Inhibitor 1, ERRFI1 ELISA Kit

SKU: E5259Hu

Size:96 Tests-1 Kit

Background:Negative regulator of EGFR signaling in skin morphogenesis. Acts as a negative regulator for several EGFR family members, including ERBB2, ERBB3 and ERBB4. Inhibits EGFR catalytic activity by interfering with its dimerization. Inhibits autophosphorylation of EGFR, ERBB2 and ERBB4. Important for normal keratinocyte proliferation and differentiation. Plays a role in modulating the response to steroid hormones in the uterus. Required for normal response to progesterone in the uterus and for fertility. Mediates epithelial estrogen responses in the uterus by regulating ESR1 levels and activation. Important for regulation of endometrium cell proliferation. Important for normal prenatal and perinatal lung development (By similarity).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:ERRFI1

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.77ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Erbb Receptor Feedback Inhibitor 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9UJM3

MASS(Da):50,560

GeneID:54206

Synonyms:ERBB receptor feedback inhibitor 1;ERRFI 1;ERRFI1;MIG-6;Mitogen-inducible gene 6 protein

Gene names:ERRFI1

Standard solution:4800ng/L