Human EPCAM/Trop1 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ0755

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: EPCAM

Specificity: Natural and recombinant human EPCAM

Background: Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. Also it is involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since it is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.

Immunogen: Expression system for standard: NS0; Immunogen sequence: Q24-K265

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Uniprot ID: P16422

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 4072

Protein Name: Epithelial cell adhesion molecule

Gene Full Name: epithelial cell adhesion molecule

Synonyms: CD326; CO 17A; CO17 1A; EGP; EGP 2; EGP314; EGP34; EGP40; Ep CAM; EPCAM; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733 2; hEGP 2; hEGP314; KS 1/4 antigen; KS1/4; KSA; M1S2; M4S1; MIC18; MK 1; TACST 1; TACSTD1; TROP1