Human Endorepellin/HSPG2 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ1760

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: HSPG2

Specificity: Natural and recombinant human Endorepellin/HSPG2

Background: Perlecan (PLC) also known as HSPG2, is a protein that in humans is encoded by the HSPG2 gene. It is mapped to 1p36.12. Perlecan is highly conserved across species and the available data indicate that it has evolved from ancient ancestors by gene duplication and exonshuffling. Perlecan is a key component of the vascular extracellular matrix, here it interacts with a variety of other matrix components and helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. Perlecan can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation.

Immunogen: Expression system for standard: NS0; Immunogen sequence: E3687-S4391

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Reconstitution:

Reference:

Uniprot ID: P98160

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 3339

Protein Name: Basement membrane-specific heparan sulfate proteoglycan core protein

Gene Full Name: heparan sulfate proteoglycan 2

Synonyms: heparan sulfate proteoglycan 2; HSPG; HSPG2; Perlecan; PLC; PRCAN; SJA; SJS; SJS1