Human Emerin, EMD ELISA Kit

SKU: E4734Hu

Size:96 Tests-1 Kit

Background:Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.

Research_area:Others

Applications:ELISA

Target_protein:EMD

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.11ng/ml

Detection range:0.2-100ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Emerin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P50402

MASS(Da):28,994

GeneID:2010

Synonyms:EMD;Emerin

Gene names:EMD

Standard solution:128ng/ml