Human E3 Ubiquitin-protein Ligase Mdm2, MDM2 ELISA Kit

SKU: E5213Hu

Size:96 Tests-1 Kit

Background:Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene. Mdm2 is an important negative regulator of the p53 tumor suppressor. Mdm2 protein functions both as an E3 ubiquitin ligase that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor suppressor and as an inhibitor of p53 transcriptional activation.

Research_area:Cell Biology

Applications:ELISA

Target_protein:MDM2

Reactivity:Human

Assay type:Sandwich

Sensitivity:9.33ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:E3 ubiquitin-protein ligase Mdm2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q00987

MASS(Da):55,233

GeneID:4193

Synonyms:ACTFS;Double minute 2 protein;E3 ubiquitin-protein ligase Mdm2;hdm2;HDMX;LSKB;MDM2;Oncoprotein Mdm2;p53-binding protein Mdm2;RING-type E3 ubiquitin transferase Mdm2

Gene names:MDM2

Standard solution:4800ng/L