Human Dual Specificity Phosphatase 6,DUSP6 ELISA KIT

SKU: E2503Hu

Size:96 Tests-1 Kit

Background:Inactivates MAP kinases. Has a specificity for the ERK family (PubMed:9858808). Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia (By similarity). Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain (By similarity). Promotes cell differentiation by regulating MAPK1/MAPK3 activity and regulating the expression of AP1 transcription factors (PubMed:29043977). {ECO:0000250|UniProtKB:Q9DBB1, ECO:0000269|PubMed:29043977, ECO:0000269|PubMed:8670865}.

Research_area:

Applications:ELISA

Target_protein:DUSP6

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Dual Specificity Phosphatase 6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q16828

MASS(Da):42320

GeneID:1848

Synonyms:DUSP6 MKP3 PYST1

Gene names:DUSP6

Standard solution:24ng/ml