Human Diacylglycerol-O-Acyltransferase Homolog 2, DGAT2 ELISA Kit

SKU: E2653Hu

Size:96 Tests-1 Kit

Background:Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides (PubMed: 27184406). Probably plays a central role in cytosolic lipid accumulation. In liver, is primarily responsible for incorporating endogenously synthesized fatty acids into triglycerides (By similarity). Functions also as an acyl-CoA retinol acyltransferase (ARAT) (By similarity). Also able to use 1-monoalkylglycerol (1-MAkG) as an acyl acceptor for the synthesis of monoalkyl-monoacylglycerol (MAMAG) (PubMed: 28420705).

Research_area:Tags & Cell Markers

Applications:ELISA

Target_protein:DGAT2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.12ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Diacylglycerol-O-Acyltransferase Homolog 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q96PD7

MASS(Da):43,831

GeneID:84649

Synonyms:Acyl-CoA retinol O-fatty-acyltransferase;ARAT;DGAT 2;DGAT2;Diacylglycerol O-acyltransferase 2;Diglyceride acyltransferase 2;Retinol O-fatty-acyltransferase

Gene names:DGAT2

Standard solution:64ng/ml