Human Cytoplasmic Aconitate Hydratase, ACO1 ELISA Kit

SKU: E4338hu

Size:96 Tests-1 Kit

Background:Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding. Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:ACO1

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.03ng/mL

Detection range:2-32ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Cytoplasmic Aconitate Hydratase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P21399

MASS(Da):98,399

GeneID:48

Synonyms:ACO 1;ACO1;Aconitase;Citrate hydro-lyase;Cytoplasmic aconitate hydratase;Ferritin repressor protein;IRE-BP 1;Iron regulatory protein 1;Iron-responsive element-binding protein 1;IRP1

Gene names:ACO1

Standard solution:64ng/mL