Human Coronin 2A, CORO2A ELISA Kit

SKU: E2446Hu

Size:96 Tests-1 Kit

Background:Coronin, actin binding protein, 2A is a protein that in humans is encoded by the CORO2A gene. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:CORO2A

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.024ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Coronin 2A

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q92828

MASS(Da):59,763

GeneID:7464

Synonyms:CLIPINB;CORO2A;Coronin-2A;IR10;WD repeat-containing protein 2;WDR2

Gene names:CORO2A

Standard solution:16ng/ml