Human Contactin 1,CNTN1 ELISA KIT

SKU: E2261Hu

Size:96 Tests-1 Kit

Background:Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:CNTN1

Reactivity:Human

Assay type:Sandwich

Sensitivity:40.69ng/L

Detection range:75-4800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Contactin 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q12860

MASS(Da):113320

GeneID:1272

Synonyms:CNTN1

Gene names:CNTN1

Standard solution:9600ng/L