Human Chymase ELISA Kit PicoKine®

SKU: EK1229

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: CMA1

Specificity: Natural and recombinant human Chymase

Background: Chymase is a major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. Chymase is mapped to 14q12. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II.

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Uniprot ID: P23946

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 1215

Protein Name:

Gene Full Name: Chymase

Synonyms: Chymase; 3.4.21.39; Alpha-chymase; Mast cell protease I; CMA1; CYH, CYM