Human BPI fold-containing family A member 1,BPIFA1 ELISA KIT

SKU: E7483Hu

Size:96 Tests-1 Kit

Background:Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC) (PubMed:25223608). Plays a role in the innate immune responses of the upper airways (PubMed:23499554, PubMed:23132494). Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae (PubMed:23499554, PubMed:23132494, PubMed:27145151). Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus (PubMed:24124190, PubMed:24043776). Plays a role in the airway inflammatory response after exposure to irritants (PubMed:11425234). May attract macrophages and neutrophils (PubMed:23132494). {ECO:0000269|PubMed:11425234, ECO:0000269|PubMed:23132494, ECO:0000269|PubMed:23499554, ECO:0000269|PubMed:24043776, ECO:0000269|PubMed:24124190, ECO:0000269|PubMed:25223608, ECO:0000269|PubMed:27145151}.

Research_area:

Applications:ELISA

Target_protein:BPIFA1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.2ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:BPI fold-containing family A member 1

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NP55

MASS(Da):26713

GeneID:51297

Synonyms:BPIFA1 LUNX NASG PLUNC SPLUNC1 SPURT UNQ787/PRO1606

Gene names:BPIFA1

Standard solution:48ng/ml