Human Beta-hexosaminidase Subunit Alpha, HEXA ELISA Kit

SKU: E6554Hu

Size:96 Tests-1 Kit

Background:Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides (PubMed:11707436, PubMed:9694901, PubMed:8672428, PubMed:8123671). The isozyme S is as active as the isozyme A on the anionic bis-sulfated glycans, the chondroitin-6-sulfate trisaccharide (C6S-3), and the dermatan sulfate pentasaccharide, and the sulfated glycosphingolipid SM2 (PubMed:11707436). The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide (PubMed:11707436). Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A (PubMed:9694901, PubMed:8672428, PubMed:8123671).

Research_area:Tags & Cell Markers; Neuroscience

Applications:ELISA

Target_protein:HEXA

Reactivity:Human

Assay type:Sandwich

Sensitivity:4.91ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Beta-hexosaminidase subunit alpha

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P06865

MASS(Da):60,703

GeneID:3073

Synonyms:Beta-hexosaminidase subunit alpha;Beta-N-acetylhexosaminidase subunit alpha;HEXA;Hexosaminidase subunit A;N-acetyl-beta-glucosaminidase subunit alpha;TSD

Gene names:HEXA

Standard solution:2400ng/L