Human Atp-sensitive Inward Rectifier Potassium Channel 10, KCNJ10 ELISA Kit

SKU: E1794Hu

Size:96 Tests-1 Kit

Background:May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium Channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the Channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules.

Research_area:Neuroscience

Applications:ELISA

Target_protein:KCNJ10

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.32ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Atp-Sensitive Inward Rectifier Potassium Channel 10

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P78508

MASS(Da):42,508

GeneID:3766

Synonyms:ATP-dependent inwardly rectifying potassium Channel Kir4.1;ATP-sensitive inward rectifier potassium Channel 10;Inward rectifier K(+ Channel Kir1.2;KCNJ 10;KCNJ10;Potassium Channel, inwardly rectifying subfamily J member 10

Gene names:KCNJ10

Standard solution:4000ng/L