Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit

SKU: E6711Hu

Size:96 Tests-1 Kit

Background:ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11452359, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed: 11099417, PubMed: 11452359, PubMed: 15054092). The heterodimer with ABCG5 has ATPase activity (PubMed: 16893193, PubMed: 20210363, PubMed: 27144356).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:ABCG8

Reactivity:Human

Assay type:Sandwich

Sensitivity:12.63ng/L

Detection range:20-7000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Atp-Binding Cassette Sub-Family G Member 8

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9H221

MASS(Da):75,679

GeneID:64241

Synonyms:ABCG 8;ABCG8;ATP-binding cassette sub-family G member 8;Sterolin-2

Gene names:ABCG8

Standard solution:8000ng/L