Human Artemin ELISA Kit PicoKine®

SKU: EK1534

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: ARTN

Specificity: Natural and recombinant human Artemin

Background: Artemin, also known as enovin or neublastin, is a protein that in humans is encoded by the ARTN gene. This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. This protein has also been shown to promote tumor growth, metastasis, and drug resistance in mammary carcinoma.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: A108-G220

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Reference:

Uniprot ID: Q5T4W7

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 9048

Protein Name: Artemin

Gene Full Name: artemin

Synonyms: Artemin; Enovin; Neublastin; ARTN; EVN; NBN