Human Agouti-signaling Protein, ASIP ELISA Kit

SKU: E4916Hu

Size:96 Tests-1 Kit

Background:Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.

Research_area:Others

Applications:ELISA

Target_protein:ASIP

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.032ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Agouti-Signaling Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P42127

MASS(Da):14,515

GeneID:434

Synonyms:Agouti switch protein;Agouti-signaling protein;ASIP;ASP

Gene names:ASIP

Standard solution:24ng/ml