Human Adiponutrin,ADPN ELISA KIT

SKU: E4742Hu

Size:96 Tests-1 Kit

Background:Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA (PubMed:22560221). Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides (PubMed:15364929, PubMed:20034933, PubMed:22560221). Has hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety (PubMed:21878620). {ECO:0000269|PubMed:15364929, ECO:0000269|PubMed:20034933, ECO:0000269|PubMed:21878620, ECO:0000269|PubMed:22560221}.

Research_area:

Applications:ELISA

Target_protein:PNPLA3

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.013mg/ml

Detection range:0.05-20mg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Adiponutrin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9NST1

MASS(Da):52865

GeneID:80339

Synonyms:PNPLA3 ADPN C22orf20

Gene names:PNPLA3

Standard solution:24mg/ml