Human Adapter Molecule Crk, CRK ELISA Kit

SKU: E4066hu

Size:96 Tests-1 Kit

Background:Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1. [Isoform Crk-II]: Regulates cell adhesion, spreading and migration (PubMed: 31311869). Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4 (PubMed: 19004829). May regulate the EFNA5-EPHA3 signaling (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:CRK

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.021ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Adapter Molecule Crk

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P46108

MASS(Da):33,831

GeneID:1398

Synonyms:Adapter molecule crk;CRK;p38;Proto-oncogene c-Crk

Gene names:CRK

Standard solution:16ng/ml