Human 3-Hydroxy-3-methylglutaryl CoA Reductase,HMGCR ELISA KIT

SKU: E3796Hu

Size:96 Tests-1 Kit

Background:Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis (PubMed:2991281, PubMed:21357570, PubMed:6995544). HMGCR is the main target of statins, a class of cholesterol-lowering drugs (PubMed:11349148, PubMed:18540668). {ECO:0000269|PubMed:11349148, ECO:0000269|PubMed:18540668, ECO:0000269|PubMed:21357570, ECO:0000269|PubMed:2991281, ECO:0000269|PubMed:6995544}.

Research_area:

Applications:ELISA

Target_protein:HMGCR

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.97ng/ml

Detection range:1.88-120ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:3-Hydroxy-3-methylglutaryl CoA Reductase

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P04035

MASS(Da):97476

GeneID:3156

Synonyms:HMGCR

Gene names:HMGCR

Standard solution:240ng/ml