HSP27 (Phospho S78/82) rabbit pAb

SKU: ES15594

Size: 100μL

Source:Rabbit

Applications:WB; ELISA

Reactivity:Human; Mouse; Rat

Dilution:WB 1:500-2000, ELISA(peptide)1:5000-20000

Immunogen:Synthesized pospho peptide derived from human HSP27 (Phospho S78/82)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):27kD

Human_gene_id:3315

Human_swiss_prot_no:P04792

Subcellular_location:Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. .

Other_name:Heat shock protein beta-1 (HspB1;28 kDa heat shock protein;Estrogen-regulated 24 kDa protein;Heat shock 27 kDa protein;HSP 27;Stress-responsive protein 27;SRP27)

Background:The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq, Oct 2008],