HORMAD2 Antibody - Cat. #: CSB-PA836683LA01HU

SKU: CSB-PA836683LA01HU

Size :50ug

Clone Number:

Aliases:4930529M09Rik antibody; CT46.2 antibody; HORM2_HUMAN antibody; HORMA domain containing 2 antibody; HORMA domain-containing protein 2 antibody; Hormad2 antibody; MGC26710 antibody; RP23-329P17.4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8N7B1

Immunogen:Recombinant Human HORMA domain-containing protein 2 protein (14-307AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HORMAD2

Research Areas:Cell biology