hnRNP LL rabbit pAb

SKU: ES2553

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human HNRPLL. AA range:241-290

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):60kD

Human_gene_id:92906

Human_swiss_prot_no:Q8WVV9

Subcellular_location:nucleus,membrane,viral nucleocapsid,intracellular ribonucleoprotein complex,

Other_name:HNRPLL; SRRF; BLOCK24; Heterogeneous nuclear ribonucleoprotein L-like; hnRNPLL; Stromal RNA-regulating factor

Background:heterogeneous nuclear ribonucleoprotein L like(HNRNPLL) Homo sapiens HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008],