HMG-1 (Acetyl Lys12) Polyclonal Antibody

SKU: BT-AP04139

Size:100μL

Background:HMGB1 encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. High mobility group box 1 plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of HMGB1 have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:HMGB1

applications:WB, IHC-p, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:HMG-1 (Acetyl Lys12) Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):24894

UniProt accession:Human: P09429; Mouse: P63158; Rat: P63159

Synonyms:HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1

GeneID:Human: 3146; Mouse: 100862258; Rat: 25459