Histone H2A.Z (Acetyl Lys7) rabbit pAb

SKU: ES20532

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human;Mouse;Rat

Dilution:WB: 1:500-1000

Immunogen:Synthetic Peptide of Histone H2A.Z (Acetyl Lys7)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:

Observed_band(KD):14kD

Human_gene_id:3015

Human_swiss_prot_no:P0C0S5

Subcellular_location:Nucleus. Chromosome.

Other_name:H2AFZ; H2AZ; Histone H2A.Z; H2A/z

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],