HEXIM1 Antibody - Cat. #: CSB-PA984943

SKU: CSB-PA984943

Size :50ul

Clone Number:

Aliases:Cardiac lineage protein 1 antibody; CLP 1 antibody; CLP1 antibody; EDG 1 antibody; EDG1 antibody; Estrogen down-regulated gene 1 protein antibody; FLJ13562 antibody; Hexamethylene bis acetamide inducible 1 antibody; Hexamethylene bis acetamide inducible protein antibody; Hexamethylene bis acetamide inducible transcript 1 antibody; Hexamethylene bis-acetamide-inducible protein 1 antibody; HEXI1_HUMAN antibody; HEXIM 1 antibody; Hexim1 antibody; HEXIM1 protein antibody; HIS 1 antibody; HIS1 antibody; HMBA inducible antibody; MAQ 1 antibody; MAQ1 antibody; Menage a quatre 1 antibody; Menage a quatre protein 1 antibody; Protein HEXIM1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O94992

Immunogen:Fusion protein of Human HEXIM1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Background:Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bis-acetamide inducible 2 (HEXIM2) comprise a family of proteins which inhibit positive transcription elongation factor b (P-TEFb) through association with 7SK. P-TEFb is composed of a catalytic subunit, Cdk9, and either Cyclin T1 or T2 as a regulatory subunit. This complex regulates eukaryotic gene expression at the level of elongation. The C-terminal domains of HEXIM proteins interact directly with each other. Via these domains, HEXIM1 and HEXIM2 form stable homo- and hetero-oligomers, which may aid in the formation of the 7SK small nuclear ribonucleic acid particle. Despite their similar functions, HEXIM1 and HEXIM2 exhibit distinct expression patterns in various established cell lines and human tissues.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HEXIM1

Research Areas:Epigenetics and Nuclear Signaling;Cardiovascular