HDAC7 (Ab-155) Antibody - Cat. #: CSB-PA898000

SKU: CSB-PA898000

Size :100ul

Clone Number:

Aliases:DKFZP586J0917 antibody; FLJ99588 antibody; HD 7a antibody; HD7 antibody; HD7a antibody; HDAC 7 antibody; HDAC 7A antibody; Hdac7 antibody; HDAC7_HUMAN antibody; HDAC7A antibody; Histone deacetylase 7 antibody; Histone deacetylase 7A antibody; OTTHUMP00000202813 antibody; OTTHUMP00000202814 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8WUI4

Immunogen:Synthesized non-phosphopeptide derived from Human HDAC7A around the phosphorylation site of serine 155 (T-V-S(p)-E-P).

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors By similarity. May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene.

Walsh M.J., Submitted (FEB-2000).
Zelent A., Submitted (MAY-2003).
Sugano S., Nat. Genet. 36:40-45(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HDAC7

Research Areas:Epigenetics and Nuclear Signaling;Cardiovascular;Stem cells