HDAC6 Polyclonal Antibody

SKU: BT-AP03926

Size:100μL

Background:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 6 encoded by HDAC6 belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. Histone deacetylase 6 possesses histone deacetylase activity and represses transcription.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:HDAC6

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:HDAC6 Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):131431

UniProt accession:Human: Q9UBN7; Mouse: Q9Z2V5

Synonyms:HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6

GeneID:Human: 10013; Mouse: 15185