HAND2 Antibody - Cat. #: CSB-PA010126ESR2HU

SKU: CSB-PA010126ESR2HU

Size :50ul

Clone Number:

Aliases:AI225906 antibody; AI661148 antibody; autonomic nervous system and neural crest derivatives-expressed protein 2 antibody; Basic helix loop helix transcription factor HAND2 antibody; bHLHa26 antibody; Class A basic helix-loop-helix protein 26 antibody; Deciduum antibody; Deciduum heart autonomic nervous system and neural crest derivatives expressed protein 2 antibody; DHAND 2 antibody; dHAND antibody; DHAND2 antibody; Ehand 2 antibody; Ehand2 antibody; FLJ16260 antibody; HAND 2 antibody; Hand2 antibody; HAND2_HUMAN antibody; Heart and neural crest derivatives expressed 2 antibody; Heart and neural crest derivatives expressed protein 2 antibody; heart and neural crest derivatives expressed transcript 2 antibody; heart antibody; Heart- and neural crest derivatives-expressed protein 2 antibody; Hed antibody; Highly similar to dHAND M musculus antibody; MGC125303 antibody; MGC125304 antibody; Th 2 antibody; Th2 antibody; Thing 2 antibody; Thing2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P61296

Immunogen:Recombinant Human Heart- and neural crest derivatives-expressed protein 2 protein (1-217AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5\\\'-CANNTG-3\\\' (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HAND2

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cardiovascular