GUC1A rabbit pAb

SKU: ES15854

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human; Mouse

Dilution:WB 1：500-2000

Immunogen:Synthesized peptide derived from human GUC1A AA range: 63-113

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:2978

Human_swiss_prot_no:P43080

Subcellular_location:Membrane; Lipid-anchor . Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . Present at higher levels in cone than in rod outer segments (PubMed:9620085). Subcellular location is not affected by light or dark conditions. .

Other_name:

Background:This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],