GTD2A rabbit pAb

SKU: ES15862

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000

Immunogen:Synthesized peptide derived from human GTD2A AA range: 529-579

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):105kD

Human_gene_id:84163

Human_swiss_prot_no:Q86UP8

Subcellular_location:Nucleus.

Other_name:General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha)

Background:This gene is one of several closely related genes on chromosome 7 encoding proteins containing helix-loop-helix motifs. These proteins may function as regulators of transcription. The encoded protein is unique in that its C-terminus is derived from CHARLIE8 transposable element sequence. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, and loss of this locus may contribute to the cognitive phenotypes observed in this disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],