GSK3 alpha Monoclonal Antibody

SKU: BT-MCA2102

Size:100μL

Background:GSK3 alpha (Glycogen synthase kinase 3 alpha), with 483-amino acid protein (about 53kDa), belongs to the Ser/Thr family of protein kinases, Cdc2/cdkx subfamily,GSK3 subsubfamily, which also includes GSK3 beta.GSK3 is a multifunctional serine/threonine kinase that is usually inactivated by serine phosphorylation in response to extracellular cues. GSK3 is a key regulator of numerous signalling pathways, including cellular responses to Wnt, receptor tyrosine kinases and G-protein-coupled receptors and is involved in a wide range of cellular processes, ranging from glycogen metabolism to cell cycle regulation and proliferation.GSK3 alpha is implicated in the control of several regulatory proteins including glycogen synthase and transcription factors.

Research_area:Others

Target_protein:GSK3 alpha

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:6G2F1

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:GSK3 alpha

Immunogen:Purified recombinant fragment of GSK3 alpha expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P49840

Synonyms:DKFZp686D0638, GSK3A

GeneID:2931