GRK2 Monoclonal Antibody

SKU: BT-MCA3220

Size:100μL

Background:The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. (provided by RefSeq)Tissue specificity: Expressed in peripheral blood leukocytes

Research_area:Others

Target_protein:GRK2

applications:WB, IHC, ICC

Reactivity:Human, Mouse, Rat, Monkey

Clonality:Monoclonal

Clone ID:3F8

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:GRK2

Immunogen:Purified recombinant fragment of human GRK2 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):80kDa

UniProt accession:P25098

Synonyms:GRK2, BARK1, FLJ16718, BETA-ARK1, ADRBK1

GeneID:156