GREM1 Antibody, FITC conjugated - Cat. #: CSB-PA009892LC01HU

SKU: CSB-PA009892LC01HU

Size :50ug

Clone Number:

Aliases:BMP antagonist 1 antibody; Cell proliferation inducing gene 2 protein antibody; Cell proliferation-inducing gene 2 protein antibody; CKTSF1B1 antibody; colorectal adenoma and carcinoma 1 antibody; Cysteine knot superfamily 1 antibody; Cysteine knot superfamily 1; BMP antagonist 1 antibody; Cysteine knot superfamily BMP antagonist 1 antibody; DAN domain family member 2 antibody; DAND2 antibody; Down regulated in Mos-transformed cells protein antibody; Down-regulated in Mos-transformed cells protein antibody; DRM antibody; grem1 antibody; GREM1_HUMAN antibody; Gremlin 1 homolog; cysteine knot superfamily antibody; Gremlin 1 like protein antibody; Gremlin 1; cysteine knot superfamily; homolog antibody; GREMLIN antibody; Gremlin-1 antibody; Gremlin1 antibody; IHG-2 antibody; IHG2 antibody; Increased in high glucose 2 antibody; Increased in high glucose protein 2 antibody; PIG2 antibody; Proliferation inducing gene 2 antibody; proliferation inducing gene 2 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O60565

Immunogen:Recombinant Human Gremlin-1 protein (18-184AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. Down-regulates the BMP4 signaling in a dose-dependent manner (By similarity). Antagonist of BMP2; inhibits BMP2-mediated differentiation of osteoblasts (in vitro) (PubMed:27036124). Acts as inhibitor of monocyte chemotaxis. Can inhibit the growth or viability of normal cells but not transformed cells when is overexpressed (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GREM1

Research Areas:Signal transduction; Stem cells