GREM1 Antibody - Cat. #: CSB-PA168659

SKU: CSB-PA168659

Size :50ul

Clone Number:

Aliases:BMP antagonist 1 antibody; Cell proliferation inducing gene 2 protein antibody; Cell proliferation-inducing gene 2 protein antibody; CKTSF1B1 antibody; colorectal adenoma and carcinoma 1 antibody; Cysteine knot superfamily 1 antibody; Cysteine knot superfamily 1; BMP antagonist 1 antibody; Cysteine knot superfamily BMP antagonist 1 antibody; DAN domain family member 2 antibody; DAND2 antibody; Down regulated in Mos-transformed cells protein antibody; Down-regulated in Mos-transformed cells protein antibody; DRM antibody; grem1 antibody; GREM1_HUMAN antibody; Gremlin 1 homolog; cysteine knot superfamily antibody; Gremlin 1 like protein antibody; Gremlin 1; cysteine knot superfamily; homolog antibody; GREMLIN antibody; Gremlin-1 antibody; Gremlin1 antibody; IHG-2 antibody; IHG2 antibody; Increased in high glucose 2 antibody; Increased in high glucose protein 2 antibody; PIG2 antibody; Proliferation inducing gene 2 antibody; proliferation inducing gene 2 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O60565

Immunogen:Fusion protein of Human GREM1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000

Background:This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to relay the sonic hedgehog (SHH) signal from the polarizing region to the apical ectodermal ridge during limb bud outgrowth. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GREM1

Research Areas:Signal transduction?Stem cells