GRB7 Antibody - Cat. #: CSB-PA009890ESR1HU

SKU: CSB-PA009890ESR1HU

Size :50ul

Clone Number:

Aliases:B47 antibody; Epidermal growth factor receptor GRB 7 antibody; Epidermal growth factor receptor GRB-7 antibody; GRB7 adapter protein antibody; GRB7 antibody; GRB7_HUMAN antibody; Growth factor receptor bound protein 7 antibody; Growth factor receptor-bound protein 7 antibody; OTTHUMP00000164349 antibody; OTTHUMP00000164350 antibody; OTTHUMP00000164351 antibody; OTTHUMP00000164352 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14451

Immunogen:Recombinant Human Growth factor receptor-bound protein 7 protein (233-532AA)

Raised in:Rabbit

Species Reactivity:Human, Rat

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

Background:Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5\\\'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GRB7

Research Areas:Signal transduction