GR (Acetyl Lys494) Rabbit Polyclonal Antibody

SKU: BT-AP10274

Size:100μL

Background:alternative products:At least 4 isoforms| Alpha (shown here)| Alpha-B| Beta and Beta-B| are produced by alternative initiation at Met-1 and Met-27. The existence of isoform Alpha and isoform Alpha-B has been proved by mutagenesis. As the sequence environment of the 2 potential ATG initiator codons is the same for the other altrnatively spliced isoforms| alternative initiation of translation could also occur on these transcripts. Additional isoforms seem to exist|disease:Defects in NR3C1 are a cause of glucocorticoid resistance

Research_area:Cancer; Epigenetics and nuclear signaling; Signal transduction

Target_protein:NR3C1

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:GR

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):85470

UniProt accession:Human: P04150; Mouse: P06537; Rat: P06536

Synonyms:GR ;Acetyl Lys494; Glucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1

GeneID:Human: 2908; Mouse: 0; Rat: 24413