GPX4 Antibody - Cat. #: CSB-RA188594A0HU

SKU: CSB-RA188594A0HU

Size :50ul

Clone Number:9D4

Aliases:Phospholipid hydroperoxide glutathione peroxidase (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4), GPX4

Product Type:Recombinant Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P36969

Immunogen:A synthesized peptide derived from human GPX4

Raised in:

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:50-1:200

Background:Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Essential for maturation and survival of photoreceptor cells. Plays a role in a primary T cell response to viral and parasitic infection by protecting T cells from ferroptosis, a cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species, and by supporting T cell expansion.

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GPX4

Research Areas:Cancer; Metabolism; Signal transduction