GPR124 rabbit pAb

SKU: ES5457

Size: 100μL

Source:Rabbit

Applications:WB;IF;ELISA

Reactivity:Human;Mouse

Dilution:Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human GPR124. AA range:1151-1200

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):145kD

Human_gene_id:25960

Human_swiss_prot_no:Q96PE1

Subcellular_location:Cell membrane ; Multi-pass membrane protein . Cell projection, filopodium . Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact. .

Other_name:GPR124; KIAA1531; TEM5; G-protein coupled receptor 124; Tumor endothelial marker 5

Background:caution:It is uncertain whether Met-1 or Met-8 is the initiator.,domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,tissue specificity:Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.,