GNA13 antibody , Cat. # FNab10935

SKU: FNab10935

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Guanine nucleotide-binding proteins (G proteins are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG. GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1 (By similarity. Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway. Inhibits CDH1-mediated cell adhesion in process independent from Rho activation.

Immunogen: guanine nucleotide binding protein (G protein), alpha 13

Synonyms:G alpha 13, G protein subunit alpha 13, G13, GNA13

Observed MW:44 kDa

Uniprot ID:Q14344

Reactivity:Human, Mouse, Rat

Tested Application:WB, IHC, IF

Recommended dilution:WB: 1:500-1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Gene ID:

Research Area: