Glucose-6-phosphate isomerase Monoclonal Antibody

SKU: BT-MCA4514

Size:100μL

Background:Glucose-6-phosphate isomerase, or phosphoglucose isomerase, also known as GPI. It belongs to the GPI family whose members encode multifunctional phosphoglucose isomerase proteins involved in energy pathways and it is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The protein functions in different capacities inside and outside the cell. In the cytoplasm, the gene product is involved in glycolysis and gluconeogenesis, while outside the cell it functions as a neurotrophic factor for spinal and sensory neurons. Defects in GPI are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment.

Research_area:Others

Target_protein:Glucose-6-phosphate isomerase

applications:IHC, ICC

Reactivity:Human

Clonality:Monoclonal

Clone ID:1B7D7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:Glucose-6-phosphate isomerase

Immunogen:Purified recombinant fragment of human GPI expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):63kDa

UniProt accession:P06744

Synonyms:AMF, NLK, PGI, PHI, GNPI, SA-36, GPI

GeneID:2821