GLRA3 antibody , Cat. # FNab03488

SKU: FNab03488

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:9677400, PubMed:26416729). Channel characteristics depend on the subunit composition; heteropentameric channels display faster channel closure(By similarity). Plays an important role in the down-regulation of neuronal excitability(By similarity). Contributes to the generation of inhibitory postsynaptic currents(By similarity). Contributes to increased pain perception in response to increased prostaglandin E2 levels(By similarity). Plays a role in cellular responses to ethanol(By similarity).

Immunogen:glycine receptor, alpha 3

Synonyms:

Observed MW:54kd

Uniprot ID:O75311

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500-1:2000

Gene ID:8001

Research Area:Neuroscience, Signal Transduction, Developmental biology