GLP1R Polyclonal Antibody

SKU: E-AB-62762

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:GLP1R

Target Synonym:GLP1R;GLP-1;GLP-1-R;GLP-1R

Research Areas:Cardiovascular;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P43220

Accession:

Background:This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.

Concentration:1mg/mL

Immunogen:Recombinant fusion protein of human GLP1R (NP_002053.3).

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:53kDa

ObservedMW:53kDa