GCSH Polyclonal Antibody

SKU: E-AB-53060

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:GCSH

Target Synonym:GCE;GCSH;GCSH;Glycine cleavage system H protein;Glycine cleavage system H protein mitochondrial;Glycine cleavage system protein H (aminomethyl carrier);Glycine cleavage system protein H;Lipoic acid containing protein;mitochondrial;Mitochondrial glycine cleavage system H protein;NKH

Research Areas:Cancer;Metabolism;Signal transduction;Tags & Cell Markers

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P23434

Accession:

Background:Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.

Concentration:1.08 mg/mL

Immunogen:Fusion protein of human GCSH

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: