GCK Antibody - Cat. #: CSB-PA009319ESR2HU

SKU: CSB-PA009319ESR2HU

Size :50ul

Clone Number:

Aliases:ATP:D-hexose 6-phosphotransferase antibody; FGQTL3 antibody; GCK antibody; GK antibody; GLK antibody; Glucokinase antibody; Hexokinase D pancreatic isozyme antibody; Hexokinase type IV antibody; Hexokinase-4 antibody; Hexokinase-D antibody; HHF3 antibody; HK IV antibody; HK4 antibody; HKIV antibody; HXK4_HUMAN antibody; HXKP antibody; LGLK antibody; MODY2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P35557

Immunogen:Recombinant Human Glucokinase protein (1-300AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200

Background:Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GCK

Research Areas:Cancer; Metabolism; Signal transduction