GCAT Polyclonal Antibody

SKU: E-AB-18831

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: GCAT

Target Synonym: 2 amino 3 ketobutyrate CoA ligase ;2 amino 3 ketobutyrate coenzyme A ligase; mitochondrial;2-amino-3-ketobutyrate coenzyme A ligase;AKB ligase;Aminoacetone synthase;GCAT;Glycine acetyltransferase;glycine C acetyltransferase ;glycine C acetyltransferase (2 amino 3 ketobutyrate coenzyme A ligase);KBL;KLB;mitochondrial

Research Areas: Cancer;Metabolism;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O75600

Accession:

Background: The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.

Concentration: 1.02 mg/mL

Immunogen: Fusion protein of human GCAT

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 45 kDa

ObservedMW: Refer to figures