GASP-1 rabbit pAb

SKU: ES8093

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human GASP1. AA range:741-790

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:9737

Human_swiss_prot_no:Q5JY77

Subcellular_location:Cytoplasm .

Other_name:GPRASP1; GASP; KIAA0443; G-protein coupled receptor-associated sorting protein 1; GASP-1

Background:This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010],