GAR1 Antibody, FITC conjugated - Cat. #: CSB-PA878917LC01HU

SKU: CSB-PA878917LC01HU

Size :50ug

Clone Number:

Aliases:Gar1 antibody; GAR1_HUMAN antibody; H/ACA ribonucleoprotein complex subunit 1 antibody; nucleolar protein family A member 1 (H/ACA small nucleolar RNPs) antibody; Nucleolar protein family A member 1 antibody; snoRNP protein GAR1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NY12

Immunogen:Recombinant Human H/ACA ribonucleoprotein complex subunit 1 protein (1-217AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (\"psi\") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GAR1

Research Areas:Epigenetics and Nuclear Signaling