GAB2 Monoclonal Antibody

SKU: BT-MCA3941

Size:100μL

Background:This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Research_area:Neuroscience

Target_protein:GAB2

applications:IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:1F6D9

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:GAB2

Immunogen:Purified recombinant fragment of human GAB2 (AA: 332-476) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):74.5kDa

UniProt accession:Q9UQC2

Synonyms:

GeneID:9846